T CELL-MEDIATED HOST INJURY
We are studying immunopathologic roles of bystander-activated CD8+ T cells and TNF-producing Treg cells in other human viral diseases and chronic inflammatory diseases.
SENESCENCE OF T CELLS
We are studying mechanism how senescent T cells contribute to the pathogenesis of inflammatory diseases and cardiovascular diseases.
REINVIGORATION OF EXHAUSTED T CELLS
We are studying strategies to improve treatment responses of anti-PD-1, including novel target molecules and biomarkers predicting treatment responses.