Laboratory of Immunology & Infectious Diseases (LIID)

We are studying T cell responses in human viral disease and cancer, in the aspect of T cell-mediated host injury, senescence of T cells, and reinvigoration of exhausted T cells.

T cell-mediated host injury

We are studying immunopathologic roles of bystander-activated CD8+ T cells and TNF-producing Treg cells in other human viral diseases and chronic inflammatory diseases.

Senescence of T cells

We are studying mechanism how senescent T cells contribute to the pathogenesis of inflammatory diseases and cardiovascular diseases.

Reinvigoration of exhausted T cells

We are studying strategies to improve treatment responses of anti-PD-1, including novel target molecules and biomarkers predicting treatment responses.