Laboratory of Immunology & Infectious Diseases (LIID)
We are studying T cell responses in human viral disease and cancer, in the aspect of T cell-mediated host injury, senescence of T cells, and reinvigoration of exhausted T cells.
T cell-mediated host injury
We are studying immunopathologic roles of bystander-activated CD8+ T cells and TNF-producing Treg cells in other human viral diseases and chronic inflammatory diseases.
Senescence of T cells
We are studying mechanism how senescent T cells contribute to the pathogenesis of inflammatory diseases and cardiovascular diseases.
Reinvigoration of exhausted T cells
We are studying strategies to improve treatment responses of anti-PD-1, including novel target molecules and biomarkers predicting treatment responses.